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背景介紹:DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19.
別名:CADM-140 autoantigen; Clinically amyopathic dermatomyositis autoantigen 140 kDa; DEAD/H (Asp Glu Ala Asp/His) box polypeptide; DEAD/H box polypeptide; Helicard; Helicase with 2 CARD domains; Hlcd; IDDM 19; IDDM19; IFIH 1; IFIH1; IFIH1_HUMAN; Interferon induced helicase C domain containing protein 1; interferon induced with helicase C domain 1; Interferon induced with helicase C domain protein 1; Interferon-induced helicase C domain-containing protein 1; Interferon-induced with helicase C domain protein 1; MDA 5; MDA-5; Melanoma differentiation associated protein 5; Melanoma differentiation-associated gene 5; Melanoma differentiation-associated protein 5; MGC133047; Murabutide down regulated protein; Murabutide down-regulated protein; RH 116; RH116; RIG I like receptor 2; RLR 2; RNA helicase DEAD box protein 116; RNA helicase-DEAD box protein 116.
黑色素瘤分化相關蛋白5抗體,Anti-MDA5抗體簡單介紹:
產品編號:BYK-18740R
英文名稱:Anti-MDA5
中文名稱:黑色素瘤分化相關蛋白5抗體
產品規格:50ul;100ul;200ul;1ml,*
抗體來源 Rabbit or Mouse
克隆類型 Polyclonal or Monoclonal
交叉反應、產品應用 (具體交叉反應與產品應用請或添加客服直接索取)
性 狀 Lyophilized or Liquid
濃 度 1mg/ml
黑色素瘤分化相關蛋白5抗體,Anti-MDA5抗體產品信息:
博研生物小課堂:
常用激光器對應熒光素的選擇:
藍色激光器熒光素(488nm):Alexa Fluor 488、FITC、PerCP、PerCP-Cy5.5、PE、PE-Cy5.5、PE-Cy5、PE-Cy7
紅色激光器熒光素(633nm):APC、Cy5、APC-Cy5.5、APC-Cy7、Alexa Fluor 647
黃色激光器熒光素(561nm):PE、PE-Cy5.5、PE-Cy5、PE-Cy7、Cy3、Alexa Fluor 555、Alexa Fluor 594
黑色素瘤分化相關蛋白5抗體,Anti-MDA5抗體相關產品:
Anti-ACN9 ACN9蛋白抗體
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Anti-PTHrP/PTHLH 甲狀旁腺激素相關蛋白抗體
Anti-PTGEs 前列腺素E合成酶抗體
Anti-Lhx4 Lhx4蛋白抗體
Anti-PGE2 前列腺素E2抗體
Anti-PTEN/MMAC1(CT) 一種腫瘤抑制基因抗體(C端)
Anti-PTEN/MMAC1(NT) 一種腫瘤抑制基因抗體(N端)
Anti-CD66a/CEACAM1 癌胚抗原相關細胞粘附分子1抗體
Anti-ARPC4/p20-ARC 肌動蛋白相關蛋白2/3亞型4抗體
Anti-NHLH1+NHLH2 螺旋環螺旋蛋白1+2抗體
Anti-CD63/MLA1 黑色素瘤相關抗原抗體
Anti-TAS2R5 味覺受體蛋白家族2亞基5抗體
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