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背景介紹:CMBL is a 245 amino acid cytosolic protein and cysteine hydrolase that preferentially cleaves cyclic esters. A member of the dienelactone hydrolase family, CMBL is the human homolog of Pseudomonas dienelactone hydrolase, a protein that participates in the bacterial halocatechol degradation pathway. CMBL is ubiquitously expressed with high expression in liver, colon, kidney and small intestine, where it acts as a bioactivating enzyme for a prodrug type angiotensin II type 1 receptor antagonist known as olmesartan medoxomil. CMBL is inhibited by p-chloromercuribenzoate (PCMB) and is encoded by a gene that maps to human chromosome 5p15.2. Chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm, or of chromosome 5 altogether, is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
別名:LOC134147; Carboxymethylenebutenolidase homolog (Pseudomonas); Carboxymethylenebutenolidase homolog; cmbl; CMBL_HUMAN; FLJ23617
CMBL蛋白抗體,Anti-CMBL抗體簡單介紹:
產品編號:BYK-18758R
英文名稱:Anti-CMBL
中文名稱:CMBL蛋白抗體
產品規格:50ul;100ul;200ul;1ml,*
抗體來源 Rabbit or Mouse
克隆類型 Polyclonal or Monoclonal
交叉反應、產品應用 (具體交叉反應與產品應用請或添加客服直接索取)
性 狀 Lyophilized or Liquid
濃 度 1mg/ml
CMBL蛋白抗體,Anti-CMBL抗體產品信息:
博研生物小課堂:
常用激光器對應熒光素的選擇:
藍色激光器熒光素(488nm):Alexa Fluor 488、FITC、PerCP、PerCP-Cy5.5、PE、PE-Cy5.5、PE-Cy5、PE-Cy7
紅色激光器熒光素(633nm):APC、Cy5、APC-Cy5.5、APC-Cy7、Alexa Fluor 647
黃色激光器熒光素(561nm):PE、PE-Cy5.5、PE-Cy5、PE-Cy7、Cy3、Alexa Fluor 555、Alexa Fluor 594
一、流式細胞抗原染色方法
細胞表面抗原標記:細胞在各自正常分化成熟的不同階段以及活化過程中,其細胞膜表面均可表達供鑒別的特殊結構,即表面標志。流式細胞術在細胞表面分子的檢測與分析主要應用于免疫細胞及其亞群的檢測與功能分析;血液系統細胞表面標志的研究;細胞群體及細胞表面標志變化的檢測;細胞表面標志構成性質分析。
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