背景介紹：Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf142 gene product has been provisionally designated C6orf142 pending further characterization.

別名：C6orf142; MLIP; MLIP_HUMAN; Muscle enriched A type lamin interacting protein; Muscular LMNA-interacting protein; Muscular-enriched A-type laminin-interacting protein; RP11-642N5.1.  

6號染色體開放閱讀框142抗體,Anti-MLIP抗體簡單介紹：

產品編號：BYK-18952R

英文名稱：Anti-MLIP
中文名稱：6號染色體開放閱讀框142抗體

產品規格：50ul；100ul；200ul；1ml，*

抗體來源 Rabbit or Mouse

克隆類型 Polyclonal or Monoclonal

交叉反應、產品應用 （具體交叉反應與產品應用請或添加客服直接索取）

性    狀 Lyophilized or Liquid
濃    度 1mg/ml

6號染色體開放閱讀框142抗體,Anti-MLIP抗體產品信息：

博研生物小課堂：

常用激光器對應熒光素的選擇：

藍色激光器熒光素（488nm）：Alexa Fluor 488、FITC、PerCP、PerCP-Cy5.5、PE、PE-Cy5.5、PE-Cy5、PE-Cy7

紅色激光器熒光素（633nm）：APC、Cy5、APC-Cy5.5、APC-Cy7、Alexa Fluor 647

黃色激光器熒光素（561nm）：PE、PE-Cy5.5、PE-Cy5、PE-Cy7、Cy3、Alexa Fluor 555、Alexa Fluor 594

常見問題與解答

1. 高熒光強度背景

（1）熒光標記的抗體濃度應該合適，如果濃度過高，背景會因為非特異性相互作用的增加而增加。

（2）在使用*抗體之前，將樣品與過量的蛋白一起培育，如小牛血清蛋白（BSA），脫脂干奶酪，或來自于同一寄主的正常血清作為標記的第二抗體。這個步驟通過阻斷*抗體和細胞表面或胞內結構的非特異性的交互作用來降低背景。

（3）在使用*抗體之后，將樣品與5%至10%的來自于同一寄主的正常血清和作為標記的第二抗體一起培育。這個步驟會減少不必要的第二抗體與*抗體、細胞表面或胞內結構之間的交互作用。

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