背景介紹：MUS81 encodes a helix-hairpin-helix protein involved in the response to UV- and methylation-induced DNA damage in Saccharomyces cerevisiae (1). Mus81 is important for replicational stress tolerance in both budding and fission yeast (2). Specifically, Mus81 associates with Eme1 to form an endonuclease that can process stalled replication forks before they have regressed to form a Holliday junction (2–4). Mus81 associated endonuclease resolves Holliday junctions into linear duplexes by cutting across the junction exclusively on strands of like polarity (2). In addition, Mus81 protein abundance increases in cells following exposure to agents that block DNA replication (2). Mus81 is involved in the recruitment of Cds1 to aberrant DNA structures where Cds1 modulates the activity of damage tolerance enzymes (4). The gene encoding human MUS81 maps to chromosome 11q13 and encodes a 551 amino acid protein (5).

別名：Crossover junction endonuclease MUS81; FLJ21012; FLJ44872; Mus 81; MUS81; MUS81 Endonuclease Homolog; MUS81_HUMAN.  

核酸內切酶同源蛋白抗體，Anti-Mus81抗體簡單介紹：

產品編號：BYK-19109R

英文名稱：Anti-Mus81
中文名稱：核酸內切酶同源蛋白抗體

產品規格：50ul；100ul；200ul；1ml，*

抗體來源 Rabbit or Mouse

克隆類型 Polyclonal or Monoclonal

交叉反應、產品應用 （具體交叉反應與產品應用請或添加客服直接索取）

性    狀 Lyophilized or Liquid
濃    度 1mg/ml

核酸內切酶同源蛋白抗體，Anti-Mus81抗體產品信息：

博研生物小課堂：

常用激光器對應熒光素的選擇：

藍色激光器熒光素（488nm）：Alexa Fluor 488、FITC、PerCP、PerCP-Cy5.5、PE、PE-Cy5.5、PE-Cy5、PE-Cy7

紅色激光器熒光素（633nm）：APC、Cy5、APC-Cy5.5、APC-Cy7、Alexa Fluor 647

黃色激光器熒光素（561nm）：PE、PE-Cy5.5、PE-Cy5、PE-Cy7、Cy3、Alexa Fluor 555、Alexa Fluor 594

顯色觀察

免疫酶染色應注意控制：

1. 呈色質濃度和反應時間。增加成色質的量和（或）增加底物反應時間，可增加反應產物強度；著色太深可減少反應時間。

2. 過氧化物酶顯色時，H2O2濃度較大將使顯色反應過快而至背景加深；過量H2O2可能抑制酶的活性。

核酸內切酶同源蛋白抗體，Anti-Mus81抗體相關產品：

Anti-procollagen type IIA Ⅱ型膠原α1 N端前體肽抗體
Anti-NADPH 還原型輔酶Ⅱ/磷酸酰胺腺嘌呤二核苷酸抗體
Anti-CBLN3/Cerebellin 3 小腦肽3抗體
Anti-Nox4/NADH NADPH氧化酶4抗體
Anti-LSAMP 大腦邊緣系統相關膜蛋白抗體
Anti-Notch3/4 跨膜受體蛋白Notch-3抗體
Anti-CAPS1 鈣依賴分泌激活蛋白1抗體
Anti-Notch1/MOTC 跨膜受體蛋白Notch-1抗體
Anti-BEGAIN/SAPAP 大腦富含鳥苷酸激酶相關蛋白抗體
Anti-NOS-3/eNOS 一氧化氮合成酶-3（內皮型）抗體
Anti-MRP3 多藥耐藥相關蛋白3抗體
Anti-P2Y12 G蛋白偶聯嘌呤受體p2y12抗體
Anti-NOS-2/iNOS 一氧化氮合成酶-2抗體（誘導型）