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博研生物抗體，“胰島素樣生長因子結合蛋白5抗體,Anti-IGFBP5/IBP5抗體*現貨”應用于IHC、WB、 IF、IP、ELISA，質量保證，無效免費退換，另外本公司生產經營各種標記二抗、免疫印跡常用試劑、免疫組化常用試劑，咨詢！
產品介紹：
【產品名稱】：胰島素樣生長因子結合蛋白5抗體,Anti-IGFBP5/IBP5抗體*現貨
【產品類型】：一抗
【產品編號】：BYk-0406R
【相關標記】: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
【性 狀】： Lyophilized or Liquid
【濃 度】： 1mg/1ml
【亞 型】： IgG
【規 格】：0.1ml/100ug，0.2ml/200ug
【抗體來源】： Rabbit OR MOUSE
【克隆類型】： polyclonal or monoclonal
【產品用途】：科研實驗，用于免疫組化實驗，WB實驗、IF、IP、ELISA實驗，相應的標記抗體有HRP標記抗體，FITC標記，BIO等。
【貯 存】： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
【信息詳情】： IGFBP5 is one of a family of proteins that bind to insulin-like growth factors （IGFs）. IGFBP5 is a multifunctional protein which acts not only as a traditional binding protein but also functions as a growth factor independent of IGFs to stimulate bone formation. Currently there are seven named IGF-BPs that form high affinity complexes with both IGFI and IGFII. IGFBP5 is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGFI on smooth muscle cells, fibroblasts or osteoblasts. Data shows that IGFBP5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition and retarded muscle development.
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