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產(chǎn)品介紹:
【產(chǎn)品名稱】:白細胞介素4受體抗體IL-4Rα,Anti-IL-4R/CD124抗體現(xiàn)貨供應(yīng)
【產(chǎn)品類型】:一抗
【產(chǎn)品編號】:BYk-2458R
【相關(guān)標記】: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
【性 狀】: Lyophilized or Liquid
【濃 度】: 1mg/1ml
【亞 型】: IgG
【規(guī) 格】:0.1ml/100ug,0.2ml/200ug
【抗體來源】: Rabbit OR MOUSE
【克隆類型】: polyclonal or monoclonal
【產(chǎn)品用途】:科研實驗,用于免疫組化實驗,WB實驗、IF、IP、ELISA實驗,相應(yīng)的標記抗體有HRP標記抗體,F(xiàn)ITC標記,BIO等。
【貯 存】: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
【信息詳情】: This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Two transcript variants encoding different isoforms, a membrane-bound and a soluble form, have been found for this gene.
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