博研生物抗體，“整合素β5抗體,Anti-Integrin beta 5抗體*格”應(yīng)用于IHC、WB、 IF、IP、ELISA，質(zhì)量保證，無效免費(fèi)退換，另外本公司生產(chǎn)經(jīng)營各種標(biāo)記二抗、免疫印跡常用試劑、免疫組化常用試劑，咨詢！

產(chǎn)品介紹：

【產(chǎn)品名稱】：整合素β5抗體,Anti-Integrin beta 5抗體*格

【產(chǎn)品類型】：一抗

【產(chǎn)品編號】：BYk-2094R

【相關(guān)標(biāo)記】: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647

【性 狀】： Lyophilized or Liquid

【濃 度】： 1mg/1ml

【亞 型】： IgG

【規(guī) 格】：0.1ml/100ug，0.2ml/200ug

【抗體來源】： Rabbit OR MOUSE

【克隆類型】： polyclonal or monoclonal

【產(chǎn)品用途】：科研實(shí)驗(yàn)，用于免疫組化實(shí)驗(yàn)，WB實(shí)驗(yàn)、IF、IP、ELISA實(shí)驗(yàn)，相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體，F(xiàn)ITC標(biāo)記，BIO等。

【貯 存】： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

【信息詳情】： Integrins are important extracellular matrix （ECM） receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around 22 different integrins （different alpha/ beta subunit combinations） are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function. The integrin subunit beta 5 has only been associated with the alpha v subunit to form the alpha v beta 5 heterodimer. This integrin mediates cell adhesion to vitronectin and also recognizes fibronectin when the integrin is activated. This integrin is found in a variety of cells in most normal tissue.

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